Dental Materials
Volume 25, Issue 3 , Pages 360-368 , March 2009

Cytotoxicity of four categories of dental cements

  • Martina Schmid-Schwap

      Affiliations

    • Department of Prosthodontics, Bernhard Gottlieb University Clinic of Dentistry, Medical University of Vienna, Austria
    • ,
  • Alexander Franz

      Affiliations

    • Central Research Unit, Bernhard Gottlieb University Clinic of Dentistry, Medical University of Vienna, Austria
    • ,
  • Franz König

      Affiliations

    • Section of Medical Statistics, Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Austria
    • ,
  • Margit Bristela

      Affiliations

    • Department of Prosthodontics, Bernhard Gottlieb University Clinic of Dentistry, Medical University of Vienna, Austria
    • ,
  • Trevor Lucas

      Affiliations

    • Center of Anatomy and Cell Biology, Medical University of Vienna, Austria
    • ,
  • Eva Piehslinger

      Affiliations

    • Department of Prosthodontics, Bernhard Gottlieb University Clinic of Dentistry, Medical University of Vienna, Austria
    • ,
  • David C. Watts

      Affiliations

    • School of Dentistry and Photon Science Institute, University of Manchester, Manchester, UK
    • ,
  • Andreas Schedle

      Affiliations

    • Central Research Unit, Bernhard Gottlieb University Clinic of Dentistry, Medical University of Vienna, Austria
    • Corresponding Author InformationCorresponding author at: Bernhard Gottlieb University Clinic of Dentistry, Währingerstrasse 25a, Vienna A-1090, Austria. Tel.: +43 1 4277 67150; fax: +43 1 4277 67159.

Received 15 January 2008 ,Revised 15 July 2008 ,Accepted 13 August 2008.

References 

  1. Tillberg A, Järvholm B, Berglund A. Risks with dental materials. Dent Mater. 2008;24:940–943
  2. de Souza Costa CA, Hebling J, Randall RC. Human pulp response to resin cements used to bond inlay restorations. Dent Mater. 2006;22:954–962
  3. Accorinte Mde L, Loguercio AD, Reis A, Muench A, de Araújo VC. Adverse effects of human pulps after direct capping with the different components from a total-etch, three-step adhesive system. Dent Mater. 2005;21:599–607
  4. Sübay RK, Demirci M. Pulp reactions to dentin bonding agent as a direct capping agent. J Endod. 2005;31:201–204
  5. Jorge JH, Giampaolo ET, Vergani CE, Machado AL, Pavarina AC, Carlos IZ. Cytotoxicity of venture base resins: effect of water bath and microwave postpolymerization heat treatments. Int J Prosthodont. 2004;17:340–343
  6. Taira M, Nakao H, Matsumoto T, Takahasi J. Cytotoxic effect of methyl methacrylate on 4 cultured fibroblasts. Int J Prosthodont. 2000;13:311–315
  7. Sheridan PJ, Koka S, Ewoldsen NO, Lefebvre CA, Lavin MT. Cytotoxicity of denture base resins. Int J Prosthodont. 1997;10:73–77
  8. Franz A, König F, Anglmayer M, Rausch-Fan X, Gille G, Rausch W-D, et al. Cytotxic effects of packable and nonpackable dental composites. Dent Mater. 2003;19:382–392
  9. Schedle A, Franz A, Rausch-Fan XH, Spittler A, Lucas T, Samorapoompichit P, et al. Cytotoxic effects of dental composites, adhesive substances, compomers and cements. Dent Mater. 1998;14:429–440
  10. Wataha JC, Rueggeberg FA, Lapp CA, Lewis JB, Lockwood PE, Ergle JW, et al. In vitro cytotoxicity of resin-containing restorative materials after aging in artificial saliva. Clin Oral Investig. 1999;3:144–149
  11. Willershausen B, Schäfer D, Pistorius A, Schultze R, Mann W. Influence of resin-based restoration materials on cytotoxity in gingival fibroblasts. Eur J Med Res. 1999;4:149–155
  12. Messer RL, Lockwood PE, Wataha JC, Lewis JB, Norris S. Bouillaguet In vitro cytotoxicity of traditional versus contemporary dental ceramics. J Prosthet Dent. 2003;90:452–458
  13. Souza PP, Aranha AM, Hebling J, Giro EM, de Souza Costa CA. In vitro cytotoxicity and in vivo biocompatibility of contemporary resin-modified glass-ionomer cements. Dent Mater. 2006;22:838–844
  14. Franz A, Konradsson K, KÖnig F, Van Dijken JW, Schedle A. Cytotoxicity of a calcium aluminate cement in comparison with other dental cements and resin-based materials. Acta Odontol Scand. 2006;64:1–8
  15. Lonnroth EC, Dahl JE. Cytotoxicity of liquids and powders of chemically different dental materials evaluated using dimethylthiazol diphenyltetrazolium and neutral red tests. Acta Odontol Scand. 2003;61:52–56
  16. Franz A, König F, Lucas T, Watts DC, Schedle A. Cytotoxic effects of dental bonding substances as a function of degree of conversion. Dent Mater. 2009;25:232–239
  17. Ryan TA. Multiple comparisons in psychological research. Psychol Bull. 1959;56:26–47
  18. Ryan TA. Significance tests for multiple comparison of proportions, variances and other statistics. Psychol Bull. 1960;57:318–328
  19. Einot I, Gabriel KR. A study of powers of several methods of multiple comparisons. J Am Stat Assoc. 1975;70:351
  20. Welsch RE. Stepwise multiple comparison procedures. J Am Stat Assoc. 1977;72:359
  21. Nakamura M, Imai K, Oshima H, Yoshioka S, Kawahara H. Biocompatibility test of light-cured composites in vitro. Dent Mater J. 1985;4:231–237
  22. Kaga M, Ito Y, Okabe T, Oguchi H, Ota M. Quantitative evaluation by measuring affected area for cytotoxicity of dental materials. Shika Zairyo Kikai. 1990;9:591–599
  23. Schedle A, Franz A, Rausch-Fan XH, Samorapoompichit P, Boltz-Nitulescu G, Slavicek R. Cytotoxicity testing of dental materials: composite versus amalgam. Z Stomatol Suppl. 1994;6:39–42
  24. Inoue K, Arikawa H, Fujii K, Niihara H, Fujita R, Tsukada G, et al. Composite restorative resins: Part 3: Cytotoxicity test to mouse fibroblasts in culture of UV and visible light-activated composite resins. Dent Mater. 1988;7:55–61
  25. Ferracane JL, Condon JR. Rate of elution of leachable components from composite. Dent Mater. 1990;6:282–287
  26. Ferracane JL. Elution of leachable components from composites. J Oral Rehab. 1994;21:441–452
  27. Hanks CT, Anderson M, Craig RG. Cytotoxic effects of dental cements on two cell culture systems. J Oral Pathol. 1981;10:101–112
  28. Meryon SD, Stephens PG, Browne RM. A comparison of the in vitro cytotoxicity of two glass ionomer cements. J Dent Res. 1983;62:769–773
  29. Meryon SD, Browne RM. In vitro cytotoxicity of three dentine bonding agents. Cell Biochem Funct. 1984;2:43–48
  30. Welker D, Neupert G. Vergleichende in vitro Studie zellulärer Reaktionen auf lösliche bestandteile von EBA- und Phosphat-Zement. Dtsch Zahnärztl Z. 1975;30:522–526
  31. Leiskar J, Helgeland K. Toxicity of some dental cements in a cell culture system. Scand J Dent Res. 1977;85:471–479
  32. Tyas MJ. In vitro toxicity tests of zinc phosphate cement. J Oral Rehabil. 1978;5:339–347
  33. Aranha AM, Giro EM, Souza PP, Hebling J, de Souza Costa CA. Effect of curing regime on the cytotoxicity of resin-modified glass ionomer lining cements applied to an odontoblast-cell line. Dent Mater. 2006;22:864–869
  34. Spagnuolo G, Annunziata M, Rengo S. Cytotoxicity and oxidative stress caused by dental adhesive systems cured with halogen and LED lights. Clin Oral Investig. 2004;8:81–85
  35. Ozturk N, Usumez A, Usumez S, Ozturk B. Degree of conversion and surface of resin cement cured with different curing units. Quintessence Int. 2005;36:771–777
  36. Ergün G, Eğilmez F, Uçtaşli MB, Yilmaz S. Effect of light curing type on cytotoxicity of dentine-bonding agents. Int Endod J. 2007;4:216–223
  37. Darr AH, Jacobsen PH. Conversion of dual luting cements. J Oral Rehabil. 1995;22:43–47
  38. Caughman WF, Chan DC, Rueggeberg FA. Curing potential of dual-polymerizable resin cements in simulated clinical situations. J Prosthet Dent. 2001;85:479–484
  39. Hofmann N, Papsthart G, Hugo B, Klaiber B. Comparison of photo-activation versus chemical or dual curing of resin-based luting cements regarding flexural strength, modulus and surface hardness. J Oral Rehabil. 2001;28:1022–1028
  40. Spangberg LS. In vitro assessment of the toxicity of endodontic materials. Int Endod J. 1981;14:27–33
  41. Franz A, König F, Skolka A, Sperr W, Bauer P, Lucas T, et al. Cytotoxicity of resin composites as a function of interface area. Dent Mater. 2007;23:1438–1446
  42. Costa CA, Vaerten MA, Edwards CA, Hanks CT. Cytotoxic effects of current dental adhesive systems on immortalized odontoblast cell line MDPC-23. Dent Mater. 1999;15:434–441
  43. Galler K, Hiller KA, Ettl T, Schmalz G. Selective influence of dentin thickness upon cytotoxicity of dentin contacting materials. J Endod. 2005;31:396–399
  44. Schmalz G, Schuster U, Thonemann B, Barth M, Esterbauer S. Dentin barrier test with transfected bovine pulp-derived cells. J Endod. 2001;27:96–102
  45. Schedle A, Samorapoompichit P, Rausch-Fan XH, Franz A, Füreder W, Sperr WR, et al. Response of L-929 fibroblasts, human gingival fibroblasts and human tissue mast cells to various metal cations. J Dent Res. 1995;74:1513–1520

PII: S0109-5641(08)00217-0

doi: 10.1016/j.dental.2008.08.002

Dental Materials
Volume 25, Issue 3 , Pages 360-368 , March 2009

Article Tools

* Image Usage & Resolution