Dental Materials
Volume 24, Issue 8 , Pages 1036-1042 , August 2008

Plasma-arc generated light inhibits proliferation and induces apoptosis of human gingival fibroblasts in a dose-dependent manner

  • In-Yong Hwang

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Young-Ok Son

      Affiliations

    • Division of Biological Science, Chonbuk National University, Chonju 561-756, South Korea
    • Research Center of Bioactive Materials, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Ji-Hae Kim

      Affiliations

    • Research Center of Bioactive Materials, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Young-Mi Jeon

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Jong-Ghee Kim

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Choon-Bong Lee

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Jong-Sun Park

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
  • ,
  • Jeong-Chae Lee

      Affiliations

    • Graduate School of Dentistry, Institute of Oral Biosciences, Chonbuk National University, Chonju 561-756, South Korea
    • Research Center of Bioactive Materials, Chonbuk National University, Chonju 561-756, South Korea
    • Corresponding Author InformationCorresponding author at: Institute of Oral Biosciences and Research Center of Bioactive Materials, Chonbuk National University, Chonju 561-756, South Korea. Tel.: +82 63 270 4049; fax: +82 63 270 4049.

Received 22 November 2006 ,Revised 27 August 2007 ,Accepted 21 November 2007.

References 

  1. Caughman WF, Rueggeberg FA, Curtis JW. Clinical guidelines for photocuring restorative resins. J Am Dent Assoc. 1995;126:1280–1286
  2. Dunn WJ, Taloumis LJ. Polymerization of orthodontic resin cement with light-emitting diode curing units. Am J Orthod Dentofacial Orthop. 2002;122:236–241
  3. Kanca J. High-energy illumination of the truth, or the serial endorser?. J Esthet Rest Dent. 2001;13:147–148
  4. Strydom C. Polymerization and polymerization shrinkage stress: fast cure versus conventional cure. SADJ. 2005;60:252–253
  5. Cook WD. Curing efficiency and ocular hazards of dental photopolymerization sources. Biomaterials. 1986;7:449–454
  6. Chadwick RG, Traynor N, Moseley H, Gibbs N. Blue-light curing units-a dermatological hazard. Br Dent J. 1994;176:17–21
  7. Sparrow JR, Zhou J, Cai B. DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination. Invest Ophthalmol Vis Sci. 2003;44:2245–2251
  8. Gorgidze LA, Oshemmkova SA, Vorobjev IA. Blue light inhibits mitosis in tissue culture cells. Biosci Rep. 1998;18:215–224
  9. Wataha JC, Lockwood PE, Lewis JB, Rueggeberg FA, Messer RLW. Biological effects of blue light from dental curing units. Dent Mater. 2004;20:150–157
  10. King A, Gottlieb E, Brooks DG, Murphy MP, Dunaief JL. Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochem Photobiol. 2004;79:470–475
  11. Lewis JB, Wataha JC, Messer RLW, Caughman GB, Yamamoto T, Hsu SD. Blue light differentially alters cellular redox properties. J Biomed Mater Res: Appl Biomater. 2005;72B:223–229
  12. Lockwood DB, Wtaha JC, Lweis JB, Tseng WY, Messer RLW, Hsu SD. Blue light generates reactive oxygen species (ROS) differentially in tumor vs. normal epithelial cells. Dent Mater. 2005;21:683–688
  13. Kook SH, Son YO, Chung SW, Lee SA, Kim JG, Jeon YM, et al. Caspase-independent death of human osteosarcoma cells by flavonoids is driven by p53-mediated mitochondrial stress and nuclear translocation of AIF and endonuclease G. Apoptosis. 2007;12:1289–1298
  14. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding. Anal Biochem. 1976;72:248–254
  15. Rotenberg S, Lewis JB, Lockwood PE, Tseng WY, Messer RLW, Hsu SD, et al. Extracellular environment as one mediator of blue light-induced mitochondrial suppression. Dent Mater. 2006;22:759–764
  16. von Harsdorf R, Li PF, Dietz R. Signaling pathway in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation. 1999;99:2934–2941
  17. Heath-Engel HM, Shore GC. Mitochondrial membrane dynamics, cristae remodelling and apoptosis. Biochim Biophys Acta. 2006;1763:549–560
  18. Patel T, Gores GJ, Kaufmann SH. The role of proteases during apoptosis. FASEB J. 1996;10:587–597
  19. Herold C, Ganslmayer M, Ocker M, Hermann M, Geerts A, Hahn EG, et al. The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. J Hepatol. 2002;36:233–240
  20. Noda M, Wataha JC, Kaga M, Lockwood PE, Volkmann KR, Sano H. Components of dentinal adhesives modulate heat shock protein 72 expression in heat-stressed THP-1 human monocytes at sublethal concentrations. J Dent Res. 2002;81:265–269
  21. Grzelak A, Rychlik B, Bartosz G. Light-dependent generation of reactive oxygen species in cell culture media. Free Radic Biol Med. 2001;30:1418–1425
  22. Massey V. The chemical and biological versatility of riboflavin. Biochem Soc Trans. 2000;28:283–296
  23. Lu C, Bucher G, Sander W. Photoinduced interactions between oxidized and reduced lipoic acid and riboflavin (vitamin B2). Chem Phys Chem. 2004;5:47–56
  24. Cho KS, Lee EH, Choi JS, Joo CK. Reactive oxygen species-induced apoptosis and necrosis in bovine corneal endothelial cells. Invest Ophthalmol Vis Sci. 1999;40:911–919
  25. Omata Y, Lewis JB, Rotenberg S, Lockwood PE, Messer RLW, Noda M, et al. Intra- and extracellular reactive oxygen species generated by blue light. J Biomed Mater Res. 2006;77A:470–477
  26. Sen CK, Packer L. Antioxidant and redox regulation of gene transcription. FASEB J. 1996;10:709–720
  27. Kitamura Y, Ota T, Matsuoka Y, Tooyama I, Kimura H, Shimohama S, et al. Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells. Glia. 1999;25:154–164

PII: S0109-5641(07)00283-7

doi: 10.1016/j.dental.2007.11.018

Dental Materials
Volume 24, Issue 8 , Pages 1036-1042 , August 2008