Dental Materials
Volume 22, Issue 4 , Pages 353-358 , April 2006

The effects of BIS-GMA and TEG-DMA on female mouse fertility

  • Homa Darmani

      Affiliations

    • Department of Applied Biology, Faculty of Science, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan
    • Corresponding Author InformationCorresponding author. Tel.: +962 79 5978834; fax: +962 2 7278962.
  • ,
  • Ahmad S. Al-Hiyasat

      Affiliations

    • Department of Restorative Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan

Received 25 November 2004 ,Revised 7 March 2005 ,Accepted 24 April 2005.

References 

  1. Finer Y, Jaffer F, Santerre JP. Mutual influence of cholesterol esterase and pseudocholinesterase on the biodegradation of dental composites. Biomaterials. 2004;25:1787–1793
  2. Geurtsen W, Lehmann F, Sphal W, Leyhausen G. Cytotoxicity of 35 dental resin composite monomers/additives in permanent 3T3 and three human primary fibroblasts cultures. J Biomed Mater Res. 1998;41:474–480
  3. Kehe K, Reichl FX, Durner J, Walther U, Hickel R, Forth W. Cytotoxicity of dental composite components and mercury compounds in pulmonary cells. Biomaterials. 2001;22:317–322
  4. Geurtsen W. Biocompatibility of resin-modified filling materials. Crit Rev Oral Biol Med. 2000;11:333–355
  5. Hanks CT, Strawn SE, Wataha JC, Craig RG. Cytotoxic effects of resin components on cultured mammalian fibroblasts. J Dent Res. 1991;70:1450–1455
  6. Lehmann F, Leyhausen G, Spahl W, Geurtsen W. Comparative cell culture studies of the cytotoxicity of composite resin components. Dtsch Zahnäztl Z. 1993;48:651–653
  7. Yoshii E. Cytotoxic effects of acrylates and methacrylates: relationships of monomer structures and cytotoxicity. J Biomed Mater Res. 1997;37:517–524
  8. Theilig C, Tegtmeier Y, Leyhausen G, Geurtsen W. Effects of BisGMA and TEG-DMA on proliferation, migration, and tenascin expression of human fibroblasts and keratinocytes. J Biomed Mater Res. 2000;53:632–639
  9. Kostoryz EL, Tong PY, Strautman AF, Glaros AG, Eick JD, Yourtee DM. Effects of dental resins on TNF-alpha-induced ICAM-1 expression in endothelial cells. J Dent Res. 2001;80:1789–1792
  10. Engelmann J, Leyhausen G, Lleibfritz D, Geurtsen W. Effect of TEG-DMA on the intracellular glutathione concentration of human gingival fibroblasts. J Biomed Mater Res. 2002;63:746–751
  11. Stanislawski L, Lefeuvre M, Bourd K, Soheili-Majd E, Goldberg M, Perianin A. TEG-DMA-induced toxicity in human fibroblasts is associated with early and drastic glutathione depletion with subsequent production of oxygen reactive species. J Biomed Mater Res. 2003;66A:476–482
  12. Issa Y, Watts DC, Brunton PA, Waters CM, Duxbury AJ. Resin composite monomers alter MTT and LDH activity of human gingival fibroblasts in vitro. Dent Mater. 2004;20:12–20
  13. Schweikl H, Schmalz G. Triethylene glycol dimethacrylate induces large deletions in the hprt gene of V79 cells. Mutat Res. 1999;438:71–78
  14. Hemmer W, Focke M, Wantke F, Gotz M, Jarisch R. Allergic contact dermatitis to artificial fingernails prepared from UV light-cured acrylates. J Am Acad Dermatol. 1996;35:377–380
  15. Mariotti A, Soderholm KJ, Johnson S. The in vivo effects of bisGMA on murine uterine weight, nucleic acids and collagen. Eur J Oral Sci. 1998;106:1022–1027
  16. Darmani H, Al-Hiyasat AS. The resin monomer triethylene glycol dimethacrylate (TEGDMA) exerts reproductive toxicity in male mice. Rep Fert Dev; 2005;17:401–406.
  17. Rugh R. The mouse, its reproduction and development. Minneapolis: Burgess; 1968;
  18. Al-Hiyasat AS, Darmani H, Elbetieha AM. Leached components from dental composites and their effects on fertility of female mice. Eur J Oral Sci. 2004;112:267–272
  19. Vom Saal FS, Cook PS, Buchanan DL, Palanza P, Thayer K, Nagel SC, et al. A physiologically based approach to the study of Bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production and behaviour. Toxicol Indust Health. 1989;14:239–260
  20. Darmani H, Al-Hiyasat AS. Reproductive toxic effect of bisphenol A dimethacrylate in mice. J Biomed Mater Res. 2004;69A:637–643
  21. Olea N, Pulgar R, Perez P, Olea-Serrano F, Rivas A, Novello-Fertrell A, et al. Estrogenicity of resin-based composites and sealants used in dentistry. Environ Health Pers. 1996;104:298–305
  22. Al-Hiyasat AS, Darmani H, Milhem MM. Cytotoxicity evaluation of dental resin composites and their flowable derivatives. Clin Oral Investig; 2005;9(1):21–25.
  23. Chavez DJ, Anderson TL. The glycocalyx of the mouse uterine luminal epithelium during estrus, early pregnancy, the pre-implantation period, and delayed implantation. I. Acquisition of Ricinus communis I binding sites during pregnancy. Biol Reprod. 1985;32:1135–1142
  24. Abrahamsohn PA, Zorn TM. Implantation and decidualization in rodents. J Exp Zool. 1993;266:603–628
  25. Khera KS. Maternal toxicity: a possible factor in fetal malformation in mice. Teratology. 1984;29:411–416
  26. Khera KS. Maternal toxicity: a possible etiological factor in embryo-fetal deaths and fetal malformation of rodent-rabbit species. Teratology. 1985;31:129–153
  27. Khera KS. Maternal toxicity in humans and animals: effect on fetal development and criteria for detection. Teratog Carcinog Mutagen. 1987;7:287–295
  28. Perreault SD, Barbee RR, Slott VL. Importance of glutathione in the acquisition and maintenance of sperm nuclear decondensing activity in maturing hamster oocytes. Dev Biol. 1988;125:181–186
  29. Calvin HI, Grosshans K, Blake EJ. Estimation and manipulation of glutathione levels in prepuberal mouse ovaries and ova: relevance to sperm nucleus transformation in the fertilized egg. Gamete Res. 1986;14:265–275
  30. Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Mol Reprod Dev. 2003;65:254–261
  31. Kaneko T, Iuchi Y, Kawachiya S, Fujii T, Saito H, Kurachi H, et al. Alteration of glutathione reductase expression in the female reproductive organs during the estrous cycle. Biol Reprod. 2001;65:1410–1416
  32. De Matos DG, Nogueira D, Cortvrindt R, Herrera C, Adriaenssens T, Pasqualini RS, et al. Capacity of adult and prepubertal mouse oocytes to undergo embryo development in the presence of cysteamine. Mol Reprod Dev. 2003;64:214–218
  33. Laub DN, Elmagbari NO, Elmagbari NM, Hausburg MA, Gardiner CS. Effects of acetaminophen on preimplantation embryo glutathione concentration and development in vivo and in vitro. Toxicol Sci. 2000;56:150–155
  34. Gardiner CS, Reed DJ. Synthesis of glutathione in the preimplantation mouse embryo. Arch Biochem Biophys. 1995;318:30–36
  35. Harris C. Glutathione biosynthesis in the postimplantation rat conceptus in vitro. Toxicol Appl Pharmacol. 1993;120:247–256

PII: S0109-5641(05)00184-3

doi: 10.1016/j.dental.2005.04.029

Dental Materials
Volume 22, Issue 4 , Pages 353-358 , April 2006